個(gè)人簡(jiǎn)介：
????? 現(xiàn)任中山大學(xué)附屬第七醫(yī)院副研究員,，碩士生導(dǎo)師。于2017年獲得香港大學(xué)生物信息學(xué)/遺傳學(xué)博士,，并于2017-2021年在哈佛醫(yī)學(xué)院附屬Brigham and Women’s Hospital 從事博士后研究工作, 2021年3月加入中山大學(xué)附屬第七醫(yī)院科研中心任職,。目前主要研究方向包括：1.非編碼RNA對(duì)藥物治療效果的影響及預(yù)測(cè),。2.下一代測(cè)序數(shù)據(jù)分析及其算法與工具的設(shè)計(jì)開發(fā)。3.機(jī)器學(xué)習(xí)與多組學(xué)臨床數(shù)據(jù)的應(yīng)用分析,。共發(fā)表SCI論文16篇,，以（共同）第一作者及通訊作者發(fā)表論文5篇，主要發(fā)表在American Journal of Respiratory and Critical Care Medicine, Journal of Allergy and Clinical Immunology, Nucleic Acids Research, Bioinformatics等雜志上。擔(dān)任Bioinformatics, PLOS Computational Biology, BMC Genomics, Current Bioinformatics等雜志審稿人,。
教育背景：
2005/09-2009/07? 東北石油大學(xué) 計(jì)算機(jī)科學(xué)與技術(shù) 學(xué)士
2009/09-2012/07? 華東師范大學(xué) 生物醫(yī)學(xué)工程 碩士
2012/12-2017/12? 香港大學(xué) 生物信息學(xué)/遺傳學(xué) 博士
?
工作經(jīng)歷：
2017/07-2021/01? 哈佛醫(yī)學(xué)院附屬Brigham and Women’s Hospital 博士后
2021/03-今????? ?中山大學(xué)附屬第七醫(yī)院 副研究員 碩士生導(dǎo)師
?
主要研究方向:
1．非編碼RNA對(duì)藥物治療效果的影響及預(yù)測(cè),。
2．下一代測(cè)序數(shù)據(jù)分析及其算法與工具的設(shè)計(jì)開發(fā)。
3．機(jī)器學(xué)習(xí)與多組學(xué)數(shù)據(jù)的應(yīng)用分析,。
?
榮譽(yù)和獎(jiǎng)勵(lì):
2019/05? 美國(guó)胸科協(xié)會(huì)年會(huì)（ATS）優(yōu)秀獎(jiǎng)學(xué)金
2016/04? 香港大學(xué)海外學(xué)術(shù)會(huì)議基金
2010/06? IBM數(shù)據(jù)倉(cāng)庫(kù)及數(shù)據(jù)挖掘師（高階）
2009/05? 黑龍江省優(yōu)秀畢業(yè)生
2008/06? 美國(guó)大學(xué)生數(shù)學(xué)建模競(jìng)賽（MCM）一等獎(jiǎng)
2008/06? 國(guó)家獎(jiǎng)學(xué)金
?
科研論文：
1. Al Kho, A. T.#, McGeachie, M. J.#, Li, J.#, Chase, R. P., ... & Tantisira, K. G. (2021). Airway and peripheral basophil and eosinophil counts are associated with molecular pharmacogenomic endotypes of steroid response in severe asthma. Thorax. [In Press]? (IF=9.139)
?
2. Hernandez-Pacheco N, Gorenjak M, Li, J, Repnik K, … & Pino-Yanes M. (2021). Identification of ROBO2 as a Potential Locus Associated with Inhaled Corticosteroid Response in Childhood Asthma. Journal of Personalized Medicine, 11(8):733. (IF=4.945)
?
3. Li, J., Tiwari, A., Mirzakhani, H., Wang, A.L., Kho, A.T., McGeachie, M.J., Litonjua, A.A., Weiss, S.T., Tantisira, K.G. (2021). Circulating MicroRNA: Incident Asthma Prediction and Vitamin D Effect Modification. Journal of Personalized Medicine, 11(4):307. (IF=4.945)
?
4. LaBelle, J., Bowser, M., Brown, A., Farnam, L., Kho, A., Li, J., ... & Amr, S. S. (2021). Commercially available blocking oligonucleotides effectively suppress unwanted hemolysis related miRNAs in a large whole blood RNA cohort. The Journal of Molecular Diagnostics. (IF=5.578)
?
5. Tiwari, A., Wang, A. L., Li, J., Lutz, S. M., Kho, A. T., Weiss, S. T., ... & McGeachie, M. J. (2020). Seasonal Variation in miR-328-3p and let-7d-3p Are Associated With Seasonal Allergies and Asthma Symptoms in Children. Allergy, Asthma & Immunology Research, 13. (IF=5.764)
?
6. Tiwari, A., Li, J., Kho, A. T., Sun, M., Lu, Q., Weiss, S. T., ... & McGeachie, M. J. (2020). COPD-Associated miR-145-5p is Downregulated in Early Decline FEV1 Trajectories in Childhood Asthma. The Journal of Allergy and Clinical Immunology. (IF=10.792)
?
7. Hernandez-Pacheco, N., Vijverberg, S. J., Herrera-Luis, E., Li, J., Sio, Y. Y., Granell, R., ... & Farzan, N. (2020). Genome-wide association study of asthma exacerbations despite inhaled corticosteroids use. The European Respiratory Journal. (IF=16.671)
?
8. Wang, A. L., Li, J., Kho, A. T., McGeachie, M. J., & Tantisira, K. G. (2020). Enhancing the prediction of childhood asthma remission: integrating clinical factors with microRNAs. The Journal of Allergy and Clinical Immunology, S0091-6749. (IF=10.792)
?
9. Li, J., Panganiban, R., Kho, A. T., McGeachie, M. J., Farnam, L., Chase, R. P., ... & Tantisira, K. G. (2020). Circulating MicroRNAs and Treatment Response in Childhood Asthma. American Journal of Respiratory and Critical Care Medicine, (ja). (IF=21.404)
?
10. Li, J.*, Kho, A. T., Chase, R. P., Pantano, L., Farnam, L., Amr, S. S., & Tantisira, K. G.* (2020). COMPSRA: a COMprehensive Platform for Small RnA-Seq data Analysis. Scientific reports, 10(1), 1-7. (IF=4.379)
?
11. Leong, K. W., Yu, F., Adalsteinsson, V. A., Reed, S., Gydush, G., Ladas, I., Li, J., Tantisira, K. G., & Makrigiorgos, G. M. (2019). A nuclease-polymerase chain reaction enables amplification of probes used for capture-based DNA target enrichment.?Nucleic acids research,?47(22), e147. (IF=16.971)
?
12. Wang, B., Bao, S., Zhang, Z., Zhou, X., Wang, J., Fan, Y., ... & Li, J. (2018). A rare variant in MLKL confers susceptibility to ApoE ?4-negative Alzheimer's disease in Hong Kong Chinese population. Neurobiology of aging, 68, 160-e1. (IF=4.673)
?
13. Li, M.*,#, Li, J.#, Li, M. J., Pan, Z., Hsu, J. S., Liu, D. J., ... & Sham, P. C. (2017). Robust and rapid algorithms facilitate large-scale whole genome sequencing downstream analysis in an integrative framework.?Nucleic acids research. (IF=16.971)
?
14. Lv, Q., Ma, W., Liu, H., Li, J., Wang, H., Lu, F., ... & Shi, T. (2015). Genome-wide protein-protein interactions and protein function exploration in cyanobacteria. Scientific Reports, 5. (IF=4.379)
?
15. Li, J., Sham, P. C., Song, Y., & Li, M. (2015). SPS: A Simulation Tool for Calculating Power of Set‐Based Genetic Association Tests.?Genetic epidemiology. (IF=2.135)
?
16. Van der Sluis, S., Dolan, C. V., Li, J., Song, Y., Sham, P., Posthuma, D., & Li, M. X. (2015). MGAS: a powerful tool for multivariate gene-based genome-wide association analysis.?Bioinformatics,?31(7), 1007-1015.??? (IF=6.937)
?
17. Xu, F., Zhao, C., Li, Y., Li, J., Deng, Y., & Shi, T. (2011). Exploring virus relationships based on virus-host protein-protein interaction network.?BMC systems biology,?S11. (IF=2.048)
?
18. Zhao, C., Liu, H., Li, J., Deng, Y., & Shi, T. (2010). Nucleosome structure incorporated histone acetylation site prediction in arabidopsis thaliana.?BMC genomics, S7. (IF=3.969)
?
個(gè)人郵箱:
?